Model reference · open weights
biomedbert-small-embeddings is an open-weight embedding model from NeuML. biomedbert-small-embeddings (FP32) weighs 45 MB; the smallest configuration that runs it is RTX 3060 12 GB.
For self-hosting, compare this build's requirements below with the GPU you plan to rent.
Summary of the NeuML/biomedbert-small-embeddings model card, 2026-10-01
What it is
| Released by | NeuML |
|---|---|
| Released | 2026-04-28 |
| Parameters | 23M |
| VRAM | 45 MB for the weights |
What it runs on
| Card | Runs | Memory |
|---|---|---|
| RTX 3060 12 GB | fits | 11.6 GB |
| RTX 4060 Ti 16 GB | fits | 15.4 GB |
| RTX 3090 24 GB | fits | 23.4 GB |
| RTX 4090 24 GB | fits | 23.4 GB |
| RTX 5090 32 GB | fits | 31.0 GB |
| L40S 48 GB | fits | 44.0 GB |
| A100 80 GB | fits | 78.2 GB |
| H100 80 GB | fits | 78.1 GB |
| RTX PRO 6000 Blackwell 96 GB | fits | 93.8 GB |
| DGX Spark (GB10) 128 GB unified | fits | 107 GB |
| H200 141 GB | fits | 138 GB |
| B200 180 GB | fits | 176 GB |
From the model card
This is a BiomedBERT Small model fined-tuned using sentence-transformers. It maps sentences & paragraphs to a 384 dimensional dense vector space and can be used for tasks like clustering or semantic search.
The training dataset was generated using a random sample of PubMed title-abstract pairs along with similar title pairs. The training workflow was a two step distillation process as follows.
This model can be used to build embeddings databases with txtai for semantic search and/or as a knowledge source for retrieval augmented generation (RAG).
import txtai
embeddings = txtai.Embeddings(path="neuml/biomedbert-small-embeddings", content=True)
embeddings.index(documents())
# Run a query
embeddings.search("query to run")
Alternatively, the model can be loaded with sentence-transformers.
from sentence_transformers import SentenceTransformer
sentences = ["This is an example sentence", "Each sentence is converted"]
model = SentenceTransformer("neuml/biomedbert-small-embeddings")
embeddings = model.encode(sentences)
print(embeddings)
The model can also be used directly with Transformers.
from transformers import AutoTokenizer, AutoModel
import torch
# Mean Pooling - Take attention mask into account for correct averaging
def meanpooling(output, mask):
embeddings = output[0] # First element of model_output contains all token embeddings
mask = mask.unsqueeze(-1).expand(embeddings.size()).float()
return torch.sum(embeddings * mask, 1) / torch.clamp(mask.sum(1), min=1e-9)
# Sentences we want sentence embeddings for
sentences = ['This is an example sentence', 'Each sentence is converted']
# Load model from HuggingFace Hub
tokenizer = AutoTokenizer.from_pretrained("neuml/biomedbert-small-embeddings")
model = AutoModel.from_pretrained("neuml/biomedbert-small-embeddings")
# Tokenize sentences
inputs = tokenizer(sentences, padding=True, truncation=True, return_tensors='pt')
# Compute token embeddings
with torch.no_grad():
output = model(**inputs)
# Perform pooling. In this case, mean pooling.
embeddings = meanpooling(output, inputs['attention_mask'])
print("Sentence embeddings:")
print(embeddings)
Performance of this model compared to the top base models on the MTEB leaderboard is shown below. A popular smaller model was also evaluated along with the most downloaded PubMed similarity model on the Hugging Face Hub.
The following datasets were used to evaluate model performance.
Evaluation results are shown below. The Pearson correlation coefficient is used as the evaluation metric.
| Model | PubMed QA | PubMed Subset | PubMed Summary | Average |
|---|---|---|---|---|
| all-MiniLM-L6-v2 | 90.40 | 95.92 | 94.07 | 93.46 |
| biomedbert-base-colbert | 94.59 | 97.18 | 96.21 | 95.99 |
| biomedbert-base-embeddings | 94.60 | 98.39 | 97.61 | 96.87 |
| biomedbert-base-reranker | 97.66 | 99.76 | 98.81 | 98.74 |
| biomedbert-small-colbert | 93.51 | 97.20 | 95.85 | 95.52 |
| biomedbert-small-embeddings | 93.25 | 97.93 | 96.65 | 95.94 |
| biomedbert-hash-nano-embeddings | 90.39 | 96.29 | 95.32 | 94.00 |
| pubmedbert-base-embeddings | 93.27 | 97.00 | 96.58 | 95.62 |
This model is a solid performer at a small size. It even beats the original PubMedBERT Embeddings model across the board at only 20% of the parameters. It also does much better than all-MiniLM-L6-v2, a commonly used small model which is roughly the same size.
This is a great model that can be used in CPU-only setups without trading off much on the accuracy front.
SentenceTransformer(
(0): Transformer({'max_seq_length': 512, 'do_lower_case': False, 'architecture': 'BertModel'})
(1): Pooling({'word_embedding_dimension': 384, 'pooling_mode_cls_token': False, 'pooling_mode_mean_tokens': True, 'pooling_mode_max_tokens': False, 'pooling_mode_mean_sqrt_len_tokens': False, 'pooling_mode_weightedmean_toQuoted from the model card on Hugging Face. The full card is behind the Hugging Face link above.