Model reference · open weights

BioMedLM

LLMs stanford-crfm Text gen 1 build Its own licence terms 1k dl/mo

BioMedLM is an open-weight language model from stanford-crfm. BioMedLM (BF16) weighs 10.7 GB; the smallest configuration that runs it is RTX 4060 Ti 16 GB.

For self-hosting, compare this build's requirements below with the GPU you plan to rent.

  • BioMedLM is a 2.7B parameter GPT-style language model developed by Stanford CRFM and MosaicML for biomedical text generation and question answering.
  • It was trained exclusively on PubMed abstracts and full text from The Pile, achieving 50.3% accuracy on the MedQA task.
  • The model supports a context length of 1024 tokens and is released under the bigscience-bloom-rail-1.0 license.

Summary of the stanford-crfm/BioMedLM model card, 2026-10-01

What it is

Released bystanford-crfm
Released2022-12-14
VRAM10.7 GB for the weights

What it runs on

Memory and cards for BioMedLM (BF16)

10.7 GBweights, file size
328 MBcache per 1K tokens
585 MBruntime overhead, at least
1,024 tokenscontext max
CardRequests at onceContext maxMemory
1K each
RTX 3060 12 GB99311.6 GB
RTX 4060 Ti 16 GB12all 1K15.4 GB
RTX 3090 24 GB36all 1K23.4 GB
RTX 4090 24 GB35all 1K23.4 GB
RTX 5090 32 GB58all 1K31.0 GB
L40S 48 GB97all 1K44.0 GB
A100 80 GB199all 1K78.2 GB
H100 80 GB190all 1K78.1 GB
RTX PRO 6000 Blackwell 96 GB237all 1K93.8 GB
DGX Spark (GB10) 128 GB unified277all 1K107 GB
H200 141 GB369all 1K138 GB
B200 180 GB481all 1K176 GB
2× RTX 3060 12 GB
tensor parallel
33all 1K11.6 GB a card
Memory needed at each load
Requests at once1K tokens each
111.6 GB
513.0 GB
814.0 GB
1616.7 GB
3222.0 GB
6432.8 GB

One card, with vLLM's small-card settings.

From the model card

What stanford-crfm says about BioMedLM

Read the model card

Note: This model was previously known as PubMedGPT 2.7B, but we have changed it due to a request from the NIH which holds the trademark for "PubMed".

Paper: BioMedLM: A 2.7B Parameter Language Model Trained On Biomedical Text

BioMedLM 2.7B is new language model trained exclusively on biomedical abstracts and papers from The Pile. This GPT-style model can achieve strong results on a variety of biomedical NLP tasks, including a new state of the art performance of 50.3% accuracy on the MedQA biomedical question answering task.

As an autoregressive language model, BioMedLM 2.7B is also capable of natural language generation. However, we have only begun to explore the generation capabilities and limitations of this model, and we emphasize that this model’s generation capabilities are for research purposes only and not suitable for production. In releasing this model, we hope to advance both the development of biomedical NLP applications and best practices for responsibly training and utilizing domain-specific language models; issues of reliability, truthfulness, and explainability are top of mind for us.

This model was a joint collaboration of Stanford CRFM and MosaicML.

Table of Contents

Model Details

Model Description

BioMedLM 2.7B is new language model trained exclusively on biomedical abstracts and papers from The Pile. This GPT-style model can achieve strong results on a variety of biomedical NLP tasks, including a new state of the art performance of 50.3% accuracy on the MedQA biomedical question answering task.

As an autoregressive language model, BioMedLM 2.7B is also capable of natural language generation. However, we have only begun to explore the generation capabilities and limitations of this model, and we emphasize that this model’s generation capabilities are for research purposes only and not suitable for production. In releasing this model, we hope to advance both the development of biomedical NLP applications and best practices for responsibly training and utilizing domain-specific language models; issues of reliability, truthfulness, and explainability are top of mind for us.

This model was a joint collaboration of Stanford CRFM and MosaicML.

  • Developed by: Stanford CRFM, MosaicML
  • Shared by: Stanford CRFM
  • Model type: Language model
  • Language(s) (NLP): en
  • License: bigscience-bloom-rail-1.0

Uses

This model is licensed under the terms of BigScience Open RAIL-M license used for BLOOM. Please note that, among other restrictions, this license forbids use of the model (or derivatives thereof) "To provide medical advice and medical results interpretation." If you are concerned that your use case would follow under the "letter" of this restriction, but not the "spirit," you can contact us to discuss.

Direct Use

It is possible to use this model to generate text, which is useful for experimentation and understanding its capabilities. It should not be directly used for production or work that may directly impact people.

Downstream Use

The main way we have used this model is finetuning for downstream question answering tasks, and we recommend using this model that way.

Out-of-Scope Use

We do not recommend using this model for natural language generation in a production environment, finetuned or otherwise.

Bias, Risks, and Limitations

Significant research has explored bias and fairness issues with language models (see, e.g., Sheng et al. (2021)). Predictions generated by the model may include disturbing and harmful stereotypes across protected classes; identity characteristics; and sensitive, social, and occupational groups.

Recommendations

While this model is capable of generating natural language text, we have only begun to explore this capability and its limitations. Understanding these limitations is especially important in a domain like medicine. Therefore, we strongly recommend against using this model in production for natural language generation.

Training Details

Training Data

This model was trained on the Pubmed Abstracts and Full Text from The Pile.

Training Procedure

The model was trained on MosaicML Cloud, a platform designed for large workloads like LLMs. Using the Composer training library and PyTorch FSDP, it was easy to enable multi-node training across 128 A100-40GB GPUs, and the total run was completed in ~6.25 days. The model was trained with batch size=1024 and sequence length=1024 for 300B tokens using Decoupled AdamW with the following settings:

lr1.6e-4
eps1e-8
betas[0.9, 0.95]
weight decay1.6e-5

Quoted from the model card on Hugging Face. The full card is behind the Hugging Face link above.

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