Model reference · open weights

H0-mini

H0-mini is an open-weight embedding model from bioptimus. H0-mini (FP32) weighs 171 MB; the smallest configuration that runs it is RTX 3060 12 GB.

For self-hosting, compare this build's requirements below with the GPU you plan to rent.

• H0-mini is a lightweight foundation model for histology image feature extraction developed by Owkin and Bioptimus.
• It is a Vision Transformer Base/14 with 86M parameters, distilled from H-optimus-0 using DINOv2 self-supervised distillation on 43 million histology tiles.
• The model is licensed under cc-by-nc-nd-4.0.

Summary of the bioptimus/H0-mini model card, 2026-10-01

Hugging Face ↗Paper ↗