Model reference · open weights

RITA_s

LLMs lightonai Text gen 1 build Licence not stated 627 dl/mo

RITA_s is an open-weight language model from lightonai. RITA_s (FP16) weighs 170 MB; the smallest configuration that runs it is RTX 3060 12 GB.

For self-hosting, compare this build's requirements below with the GPU you plan to rent.

  • RITA_s is an autoregressive protein sequence model developed by Lighton, the OATML group at Oxford, and the Debbie Marks Lab at Harvard.
  • It is designed for text-generation tasks involving protein sequences and contains 85 million parameters.
  • The model supports a context length of 1024 tokens.

Summary of the lightonai/RITA_s model card, 2026-10-01

What it is

Released bylightonai
Released2022-04-25
Parameters85M
VRAM170 MB for the weights

What it runs on

Memory and cards for RITA_s (FP16)

170 MBweights, file size
37 MBcache per 1K tokens
467 MBruntime overhead, at least
1,024 tokenscontext max
CardRequests at onceContext maxMemory
1K each
RTX 3060 12 GB290all 1K11.6 GB
RTX 4060 Ti 16 GB391all 1K15.4 GB
RTX 3090 24 GB603all 1K23.4 GB
RTX 4090 24 GB601all 1K23.4 GB
RTX 5090 32 GB804all 1K31.0 GB
L40S 48 GB1000+all 1K44.0 GB
A100 80 GB1000+all 1K78.2 GB
H100 80 GB1000+all 1K78.1 GB
RTX PRO 6000 Blackwell 96 GB1000+all 1K93.8 GB
DGX Spark (GB10) 128 GB unified1000+all 1K107 GB
H200 141 GB1000+all 1K138 GB
B200 180 GB1000+all 1K176 GB
Memory needed at each load
Requests at once1K tokens each
1675 MB
5826 MB
8939 MB
161.2 GB
321.8 GB
643.1 GB

One card, with vLLM's small-card settings.

From the model card

What lightonai says about RITA_s

Read the model card

RITA is a family of autoregressive protein models, developed by a collaboration of Lighton, the OATML group at Oxford, and the Debbie Marks Lab at Harvard.

Model#Paramsd_modellayerslm loss uniref-100
Small85M768122.31
Medium300M1024242.01
Large680M1536241.82
XLarge1.2B2048241.70

For full results see our preprint: https://arxiv.org/abs/2205.05789

Usage

Instantiate a model like so:

from transformers import AutoModel, AutoModelForCausalLM
model = AutoModelForCausalLM.from_pretrained("lightonai/RITA_s, trust_remote_code=True")
tokenizer = AutoTokenizer.from_pretrained("lightonai/RITA_s")

for generation we support pipelines:

from transformers import pipeline
rita_gen = pipeline('text-generation', model=model, tokenizer=tokenizer)
sequences = rita_gen("MAB", max_length=20, do_sample=True, top_k=950, repetition_penalty=1.2,
                     num_return_sequences=2, eos_token_id=2)
for seq in sequences:
    print(f"seq: {seq['generated_text'].replace(' ', '')}")

How to cite

@article{hesslow2022rita,
  title={RITA: a Study on Scaling Up Generative Protein Sequence Models},
  author={Hesslow, Daniel and Zanichelli, Niccol{\'o} and Notin, Pascal and Poli, Iacopo and Marks, Debora},
  journal={arXiv preprint arXiv:2205.05789},
  year={2022}
}

Quoted from the model card on Hugging Face. The full card is behind the Hugging Face link above.

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